After data is ingested to a Data Lakehouse, what happens if the data is structurally modified by a process outside of Infoworks and the metastore records are changed? Will Infoworks detect the divergence?

It is not recommended to modify the tables ingested by any process which is outside Infoworks as we store and main some Infoworks audit-related columns along with the ingested data. Infoworks will not detect any such changes to the metastore.